Isopropanol → 2-Chloro-3,3,4,4-tetrafluorocyclobutenyl isopropyl ether

反応式

[OH-].[Na+].Cl[C:4]1[C:7]([F:9])([F:8])[C:6]([F:11])([F:10])[C:5]=1[Cl:12].[CH:13]([OH:16])([CH3:15])[CH3:14]>>[CH:13]([O:16][C:4]1[C:7]([F:9])([F:8])[C:6]([F:11])([F:10])[C:5]=1[Cl:12])([CH3:15])[CH3:14]

参加物

反応物 3

HCID 3776Isopropanol

HCID 14798Sodium Hydroxide

HCID 1362201,2-Dichlorotetrafluorocyclobutene-1

生成物 1

HCID 199110632-Chloro-3,3,4,4-tetrafluorocyclobutenyl isopropyl ether

実験手順

200 g (5 mol) of powdered sodium hydroxide are metered into a solution of 786 g (3.94 mol) of 1,2-dichloro-3,3,4,4-tetrafluorocyclobutene and 328 g (5.47 mol) of technical grade isopropanol at -10° C. The mixture is stirred for a further 2 hours, the solid is filtered off with suction and the filtrate is distilled.