HCID 19908244、化合物 → HCID 19908238、化合物
反応式
[BrH:1].C([CH:9]1[NH:17][CH2:16][CH2:15][C:14]2[CH2:13][NH:12][CH2:11][C:10]1=2)C1C=CC=CC=1.[H][H]>C(O)(=O)C.[Pd]>[BrH:1].[BrH:1].[C:10]12[CH2:11][NH:12][CH2:13][C:14]=1[CH2:15][CH2:16][NH:17][CH2:9]2参加物
5
実験手順
0.7 g of N3 -(benzyl)-3,8-diazabicyclo[4.3.0]non-1(6)-ene hydrobromide, prepared in Preparation 10, was dissolved in 20 ml of 5% aqueous acetic acid solution. 0.5 g of 10% palladium chracoal in this solution was suspended and the reaction mixture was refluxed under the hydrogen stream for 7 hours. The solid was filtered off. The filtrate was concentrated under reduced pressure and dissolved in 10 ml of 48% bromic acid. By concentrating the solution under reduced pressure again, 0.5 g of the title compound was obtained (yield 73%).
後処理
- filtrationThe solid was filtered off
- concentrationThe filtrate was concentrated under reduced pressure
- dissolutiondissolved in 10 ml of 48% bromic acid
- concentrationBy concentrating the solution under reduced pressure again
出典と根拠
- ORDレコード
- ord-3f8e31147d3f448b8aa3a870a9cd90e1
- 出典データセット
- uspto-grants-1992_02
- 特許番号
- US05091384
反応ノート
読み込み中…