反応式
[CH3:1][C:2]([Si:5]([CH3:26])([CH3:25])[O:6][CH2:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[N:11]=[C:10](/[CH:16]=[CH:17]/[C:18]([O:20][CH2:21][CH2:22][CH2:23][CH3:24])=[O:19])[CH:9]=1)([CH3:4])[CH3:3].[H][H]>[Pd].CO>[CH3:3][C:2]([Si:5]([CH3:25])([CH3:26])[O:6][CH2:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[N:11]=[C:10]([CH2:16][CH2:17][C:18]([O:20][CH2:21][CH2:22][CH2:23][CH3:24])=[O:19])[CH:9]=1)([CH3:1])[CH3:4]参加物
5
反応物 2
生成物 1
試薬・触媒・溶媒 2
実験手順
A mixture of butyl (2E)-3-[4-({[(1,1 dimethylethyl)(dimethyl)silyl]oxy}methyl)-6-(methyloxy)-2-pyridinyl]-2-propenoate (4.84 g, 12.49 mmol) and 10% palladium on carbon in methanol (200 ml) was stirred at rt over one atmosphere of hydrogen for 3 h. The mixture was filtered through Celite and evaporated to give the desired product (4.76 g, 98%).
後処理
- filtrationThe mixture was filtered through Celite
- customevaporated
出典と根拠
- ORDレコード
- ord-fe81060b0fbe43af8449815bb57ad0f4
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07732461B2
関連ノート
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