Tetrahydrofuran → 3-[-1-(2-chlorophenyl)ethoxy]-5-[6-(hydroxymethyl)-3H-imidazo[4,5-c]pyridin-3-yl]thiophene-2-carboxamide

反応式

[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]3[c:29]([Cl:34])[cH:30][cH:31][cH:32][cH:33]3)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1)[cH:15][n:16]2)([CH3:5])([CH3:35])[CH3:36].[CH2:38]([N+:39]([CH2:40][CH2:41][CH2:42][CH3:43])([CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH3:54].[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[F-:37]>>[OH:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14](-[c:17]1[cH:18][c:19]([O:25][CH:26]([CH3:27])[c:28]3[c:29]([Cl:34])[cH:30][cH:31][cH:32][cH:33]3)[c:20]([C:22](=[O:23])[NH2:24])[s:21]1)[cH:15][n:16]2