Tetrahydrofuran → 5-(3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyridin-2-ylamino)-6-methylisoquinolin-1(2H)-one

HRID 1540219

反応式

[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][Si:31]([N-:32][Si:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][cH:15][cH:16]2.[Li+:39].[NH2:17][c:18]1[c:19]2[cH:20][cH:21][nH:22][c:23](=[O:29])[c:24]2[cH:25][cH:26][c:27]1[CH3:28]>>[c:2]1([NH:17][c:18]2[c:19]3[cH:20][cH:21][nH:22][c:23](=[O:29])[c:24]3[cH:25][cH:26][c:27]2[CH3:28])[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][cH:15][cH:16]2