2-Hydroxy-4-nitrobenzyl alcohol → 2-Hydroxy-4-nitrobenzaldehyde

HRID 15446

反応式

HRID 15446 の反応式
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-:11])=[O:10])=[CH:5][C:4]=1[OH:12]>C(Cl)(Cl)Cl.[O-2].[Mn+4].[O-2]>[OH:12][C:4]1[CH:5]=[C:6]([N+:9]([O-:11])=[O:10])[CH:7]=[CH:8][C:3]=1[CH:2]=[O:1]

参加物

4

反応物 1

HCID 118160942-Hydroxy-4-nitrobenzyl alcohol

生成物 1

HCID 755702-Hydroxy-4-nitrobenzaldehyde

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6212Chloroform溶媒

実験手順

6.0 g (35.5 mmol) of 2-(hydroxymethyl)-5-nitrophenol and 3.1 g (35.5 mmol) of activated manganese (IV) oxide in 100 ml of chloroform are heated under reflux for 20 h. The mixture is filtered through kieselguhr, concentrated and dried under high vacuum. The title compound is directly reacted further.

後処理

  1. temperatureunder reflux for 20 h
  2. filtrationThe mixture is filtered through kieselguhr
  3. concentrationconcentrated
  4. customdried under high vacuum
  5. customThe title compound is directly reacted further

出典と根拠

ORDレコード
ord-aa81303b3f8648c9bf39dd770745e02f
出典データセット
uspto-grants-2010_06
特許番号
US07732477B2

関連ノート

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