Pyridine → 2-[4-(5-Bromo-3-methylpyrid-2-yl)butylamino]-5-(4-fluorobenzyl)-4-pyrimidone

反応式

[Br:1][c:2]1[cH:3][c:4]([CH3:13])[c:5]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[n:6][cH:7]1.[F:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][c:20]2[c:21](=[O:28])[nH:22][c:23]([S:26][CH3:27])[n:24][cH:25]2)[cH:29][cH:30]1.[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[Br:1][c:2]1[cH:3][c:4]([CH3:13])[c:5]([CH2:8][CH2:9][CH2:10][CH2:11][NH:12][c:23]2[nH:22][c:21](=[O:28])[c:20]([CH2:19][c:18]3[cH:17][cH:16][c:15]([F:14])[cH:30][cH:29]3)[cH:25][n:24]2)[n:6][cH:7]1

参加物

反応物 3

HCID 1049Pyridine

HCID 130942724-(5-Bromo-3-methyl-2-pyridinyl)butylamine

HCID 202628785-(4-Fluorobenzyl)-2-methylthio-4-pyrimidone

生成物 1

HCID 202690672-[4-(5-Bromo-3-methylpyrid-2-yl)butylamino]-5-(4-fluorobenzyl)-4-pyrimidone

出典と根拠

ORDレコード: ord-e1a7012eb4774bb1ab23b72e3ca42b44
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…