2-Aminopropanol → 2'-Fluoro-5-(2-isopropyl-2H-pyrazol-3-yl)-4'-methyl-biphenyl-3-carboxylic acid (2-hydroxy-1-methyl-ethyl)-amide
反応式
[CH3:1][CH2:2][N:3]=[C:4]=[N:5][CH2:6][CH2:7][CH2:8][N:9]([CH3:10])[CH3:11].[CH3:47][N:48]1[CH2:49][CH2:50][CH2:51][C:52]1=[O:53].[Cl:59][CH2:60][Cl:61].[F:12][c:13]1[c:14](-[c:20]2[cH:21][c:22]([C:34](=[O:35])[OH:36])[cH:23][c:24](-[c:26]3[n:27]([CH:31]([CH3:32])[CH3:33])[n:28][cH:29][cH:30]3)[cH:25]2)[cH:15][cH:16][c:17]([CH3:19])[cH:18]1.[NH2:54][CH:55]([CH2:56][OH:57])[CH3:58].[OH:37][n:38]1[c:39]2[c:40]([cH:41][cH:42][cH:43][cH:44]2)[n:45][n:46]1>>[F:12][c:13]1[c:14](-[c:20]2[cH:21][c:22]([C:34](=[O:35])[NH:54][CH:55]([CH2:56][OH:57])[CH3:58])[cH:23][c:24](-[c:26]3[n:27]([CH:31]([CH3:32])[CH3:33])[n:28][cH:29][cH:30]3)[cH:25]2)[cH:15][cH:16][c:17]([CH3:19])[cH:18]1
