Dimethylformamide → tert-butyl N-[3-[3-[2-[tert-butyl(diphenyl)silyl]oxypropanoyl]-5-(3-fluorophenyl)-2-phenyl-1,3,4-thiadiazol-2-yl]propyl]carbamate

反応式

[C:30]([CH3:31])([CH3:32])([CH3:33])[Si:34]([O:35][CH:36]([C:37](=[O:38])[OH:39])[CH3:40])([c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)[c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH:86]([N:87]([CH2:88][CH3:89])[CH:90]([CH3:91])[CH3:92])([CH3:93])[CH3:94].[F:1][c:2]1[cH:3][c:4]([C:8]2=[N:9][NH:10][C:11]([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)([CH2:19][CH2:20][CH2:21][NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[S:12]2)[cH:5][cH:6][cH:7]1.[O:95]=[CH:96][N:97]([CH3:98])[CH3:99].[P-:53]([F:54])([F:55])([F:56])([F:57])([F:58])[F:59].[n:60]1([O:61][P+:62]([N:63]2[CH2:64][CH2:65][CH2:66][CH2:67]2)([N:68]2[CH2:69][CH2:70][CH2:71][CH2:72]2)[N:73]2[CH2:74][CH2:75][CH2:76][CH2:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][c:83]2[n:84][n:85]1>>[F:1][c:2]1[cH:3][c:4]([C:8]2=[N:9][N:10]([C:37]([CH:36]([O:35][Si:34]([C:30]([CH3:31])([CH3:32])[CH3:33])([c:41]3[cH:42][cH:43][cH:44][cH:45][cH:46]3)[c:47]3[cH:48][cH:49][cH:50][cH:51][cH:52]3)[CH3:40])=[O:38])[C:11]([c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)([CH2:19][CH2:20][CH2:21][NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[S:12]2)[cH:5][cH:6][cH:7]1