Water → Tert-butyl 4-(chloromethyl)-4-cyanopiperidine-1-carboxylate

反応式

[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][CH:18]([C:21]#[N:22])[CH2:19][CH2:20]1.[CH3:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl:23][CH2:24][Br:25].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[OH2:26]>>[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13](=[O:14])[N:15]1[CH2:16][CH2:17][C:18]([C:21]#[N:22])([CH2:24][Cl:23])[CH2:19][CH2:20]1