HCID 13070643、化合物 → HCID 12168430、化合物
反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[C:10](=[O:11])[O:9][CH:8]2[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[H][H]>C(O)C.[Pd]>[CH2:8]([C:7]1[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[C:12]=1[C:10]([OH:11])=[O:9])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1参加物
5
実験手順
The phthalide (30 g.) is dissolved in ethanol (500 ml.) by warming, 5% palladium-on-charcoal (3 g.) is added and the solution is hydrogenated until hydrogen uptake ceases. After removal of the catalyst by filtration, the ethanol is evaporated, and the residue is crystallised from chloroform-petroleum ether (b.p. 60°-80°C.) to give 2-benzyl-6-methoxy-benzoic acid m.p. 159°-161°C.
後処理
- temperatureby warming
- customAfter removal of the catalyst
- filtrationby filtration
- customthe ethanol is evaporated
- customthe residue is crystallised from chloroform-petroleum ether (b.p. 60°-80°C.)
出典と根拠
- ORDレコード
- ord-01cb458460c54b6e8075a8bb66180d8b
- 出典データセット
- uspto-grants-1976_09
- 特許番号
- US03979513
反応ノート
読み込み中…