2,6-Xylyl isocyanate → N-(1,3-Dimethyl-4-oxoimidazolidin-2-ylidene)-N'-(2,6-dimethylphenyl)urea

HRID 1576837

反応式

HRID 1576837 の反応式
[CH3:1][N:2]1[CH2:6][C:5](=[O:7])[N:4]([CH3:8])[C:3]1=[NH:9].[CH3:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([CH3:17])[C:12]=1[N:18]=[C:19]=[O:20]>O1CCCC1>[CH3:1][N:2]1[CH2:6][C:5](=[O:7])[N:4]([CH3:8])[C:3]1=[N:9][C:19]([NH:18][C:12]1[C:11]([CH3:10])=[CH:16][CH:15]=[CH:14][C:13]=1[CH3:17])=[O:20]

参加物

4

反応物 2

HCID 987872,6-Xylyl isocyanateHCID 140604272-Imino-1,3-dimethylimidazolidin-4-one

生成物 1

HCID 54230876N-(1,3-Dimethyl-4-oxoimidazolidin-2-ylidene)-N'-(2,6-dimethylphenyl)urea

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

A mixture of 6.35 g (0.050 mole) of 1,3-dimethyl-2-iminoimidazolidin-4-one and 7.25 g (0.050 mole) of 2,6-dimethylphenylisocyanate in 75 ml. of dry tetrahydrofuran is stirred at room temperature for two hours followed by refluxing it for thirty minutes. The reaction mixture is evaporated in vacuo to give a solid, which is crystallized from tetrahydrofuran-ether. Two more recrystallizations from the same solvent mixture gives pure product, 1-(1,3-dimethyl-4-oxo-2-imidazolidinylidene)-3-(2,6-dimethylphenyl) urea; m.p. 115.5°-118.5°C.

後処理

  1. temperatureby refluxing it for thirty minutes
  2. customThe reaction mixture is evaporated in vacuo
  3. customto give a solid, which
  4. customis crystallized from tetrahydrofuran-ether
  5. customTwo more recrystallizations from the same solvent mixture

出典と根拠

ORDレコード
ord-12b6665c574c4cdba7d9f873b7be165b
出典データセット
uspto-grants-1976_09
特許番号
US03983135

関連ノート

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