Acetone → 1-Allyloxycarbonyl-2-amino-4,5-dicyanoimidazole

HRID 1576951ノート

反応式

HRID 1576951 の反応式
[NH2:1][C:2]1[NH:3][C:4]([C:9]#[N:10])=[C:5]([C:7]#[N:8])[N:6]=1.Cl[C:12]([O:14][CH2:15][CH:16]=[CH2:17])=[O:13].CC(C)=O.[OH-].[Na+]>O>[CH2:15]([O:14][C:12]([N:3]1[C:4]([C:9]#[N:10])=[C:5]([C:7]#[N:8])[N:6]=[C:2]1[NH2:1])=[O:13])[CH:16]=[CH2:17]

参加物

6

反応物 4

HCID 180AcetoneHCID 14798Sodium HydroxideHCID 18052Allyl chloroformateHCID 1704461H-Imidazole-4,5-dicarbonitrile, 2-amino-

生成物 1

HCID 215104281-Allyloxycarbonyl-2-amino-4,5-dicyanoimidazole

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

2 g of 2-amino-4,5-dicyanoimidazole and 2 g of allyl chloroformate were added to 20 ml of acetone and further 3 ml of water solution containing 20% of sodium hydroxide was added dropwise to it under stirring at a temperature of 15° to 20°C. After the resulting solution was stirred during an hour at a room temperature, it was poured into ice-water and thereby white crystal was separated out.

後処理

  1. additionwas added dropwise to it
  2. stirringAfter the resulting solution was stirred during an hour at a room temperature
  3. customwhite crystal was separated out

出典と根拠

ORDレコード
ord-4693d9867d6c469b84c78e77938f2f51
出典データセット
uspto-grants-1976_09
特許番号
US03983241

反応ノート

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