Acetone → HCID 12760709、化合物

HRID 1577692ノート

反応式

HRID 1577692 の反応式
[OH:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[C:3]([OH:5])=[O:4].[CH3:15][C:16]([CH3:18])=O.S(=O)(=O)(O)O.C(=O)([O-])[O-].[Na+].[Na+]>O>[C:12]([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:2]1[C:3](=[O:5])[O:4][C:16]([CH3:18])([CH3:15])[O:1]1)([OH:14])=[O:13]

参加物

6

反応物 4

HCID 180AcetoneHCID 1118Sulfuric AcidHCID 10340Sodium CarbonateHCID 127607082-Hydroxynonanedioic acid

生成物 1

HCID 12760709HCID 12760709、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A stirred mixture of 10.2 g. of 2-hydroxynonanedioic acid, 50 ml. of acetone, 75 ml. of petroleum ether (b.p. 30°-55° C.), and 0.25 ml. of sulfuric acid is heated at reflux for 7 hours with azeotropic removal of water. The stirred mixture is treated with 0.59 g. of sodium carbonate and diluted with petroleum ether. The solution is decanted from solid and concentrated to give 9.4 g. of oil; pmr (CDCl3) δ1.58 and 1.63 (gem-dimethyl group).

後処理

  1. additionA stirred mixture of 10.2 g
  2. additionThe stirred mixture is treated with 0.59 g
  3. customThe solution is decanted from solid
  4. concentrationconcentrated
  5. customto give 9.4 g

出典と根拠

ORDレコード
ord-4604a47cb8c44d98b7523c9c2b0f6433
出典データセット
uspto-grants-1981_09
特許番号
US04288633

反応ノート

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