Hydrogen Peroxide → Cyclopentane, 1-acetyl-1,2-epoxy-

HRID 1578807

反応式

HRID 1578807 の反応式
[C:1]([C:4]1[CH2:8][CH2:7][CH2:6][CH:5]=1)(=[O:3])[CH3:2].[OH:9]O.[OH-].[Na+]>CO.O>[C:1]([C:4]12[O:9][CH:5]1[CH2:6][CH2:7][CH2:8]2)(=[O:3])[CH3:2]

参加物

6

反応物 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1929251-Acetylcyclopentene

生成物 1

HCID 537123Cyclopentane, 1-acetyl-1,2-epoxy-

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

A solution of 11.02 g of 1-acetyl-cyclopent-1-ene in 50 ml of methanol is cooled to -10°C and mixed with 28.8 ml of perhydrol within 5 minutes. In the course of 1 hour, while stirring and cooling, 8.25 ml of 6N-sodium hydroxide solution are added, the whole is stirred for 1/2 hour at room temperature, diluted with 125 ml of water and extracted with pentane. The pentane solution is washed neutral with sodium chloride solution and the pentane is distilled off through a Vigreux column. The residue is distilled under 10 mm Hg pressure, to yield 1-acetyl-1,2-epoxy-cyclopentane passing over at 62° - 63°C.

後処理

  1. temperaturecooling
  2. stirringthe whole is stirred for 1/2 hour at room temperature
  3. extractionextracted with pentane
  4. washThe pentane solution is washed neutral with sodium chloride solution
  5. distillationthe pentane is distilled off through a Vigreux column
  6. distillationThe residue is distilled under 10 mm Hg pressure

出典と根拠

ORDレコード
ord-c72dce79878e4d71943d180cc5d16560
出典データセット
uspto-grants-1976_02
特許番号
US03939207

関連ノート

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