Methyl iodide → HCID 20560022、化合物

反応式

[I-:1].[NH+]1C=CC=C[CH:3]=1.[CH:8]([NH:10][C:11]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][C:12]=1[CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1)=[O:9].CI.C(NC1C=CC=CC=1CCC1C=CC=CN=1)=O>>[I-:1].[CH:8]([NH:10][C:11]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][C:12]=1[CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N+:16]=1[CH3:3])=[O:9]

参加物

反応物 4

HCID 6328Methyl iodide

HCID 20559958HCID 20559958、化合物

HCID 20559985HCID 20559985、化合物

HCID 21863515PyridiuM iodide

生成物 1

HCID 20560022HCID 20560022、化合物収率 95%

実験手順

The pyridinium iodide is obtained by treating 2-(2-formamido-5-methoxyphenethyl)pyridine with methyl iodide according to the procedure described in Example 2c for 2-(o-formamidophenethyl)pyridine. Analytically pure 2-(2-formamido-5-methoxyphenethyl)-1-methylpyridinium iodide is obtained in a yield of 95% and has a melting point of 184°-186.5°C. (corr.).

出典と根拠

ORDレコード: ord-d975ef4fd150411dabc346333fbe9872
出典データセット: uspto-grants-1976_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03931195

反応ノート

読み込み中…