Water → HCID 54181831、化合物
反応式
[CH3:1][CH:2]([OH:17])[C:3]1[O:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.O>[Pd].CO>[CH3:1][CH:2]([OH:17])[C:3]1[O:7][C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1参加物
5
実験手順
A mixture of 79 g (0.34 mole) of the compound of Example I, 1 tsp. of 5% Pd/C, 50% H2O, and 500 ml of methanol was shaken under hydrogen pressure with the theoretical amount of H2 being absorbed. The catalyst was removed by filtration, and the filtrate was taken to near dryness on a Calab evaporator. The resulting solid was filtered and air-dried to yield 49 g (71%) of title compound. An analytical sample was prepared by recrystallizing a sample twice from ethanol/charcoal, m.p. 100°-104°.
後処理
- customabsorbed
- customThe catalyst was removed by filtration
- customon a Calab evaporator
- filtrationThe resulting solid was filtered
- customair-dried
出典と根拠
- ORDレコード
- ord-33b955db45094f47a9e950065cea1364
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03931247
反応ノート
読み込み中…