Thionyl Chloride → 3-(3'-p-Chlorobenzoyl-phenyl)-propionyl chloride

反応式

[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([C:6]([C:8]2[CH:9]=[C:10]([CH2:14][CH2:15][C:16](O)=[O:17])[CH:11]=[CH:12][CH:13]=2)=[O:7])=[CH:4][CH:3]=1.S(Cl)([Cl:23])=O>>[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([C:6]([C:8]2[CH:9]=[C:10]([CH2:14][CH2:15][C:16]([Cl:23])=[O:17])[CH:11]=[CH:12][CH:13]=2)=[O:7])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 214956243-(3'-p-Chlorobenzoyl-phenyl)-propionic acid

生成物 1

HCID 214956473-(3'-p-Chlorobenzoyl-phenyl)-propionyl chloride

実験手順

6.96 g of 3-(3'-p-chlorobenzoyl-phenyl)-propionic acid and 70 ml of thionyl chloride were refluxed for 3 hours and then evaporated to dryness. The residue was taken up in 100 ml of benzene and evaporated to dryness to obtain 8.7 g of 3-(3'-p-chlorobenzoyl-phenyl)-propionyl chloride which was used as is.

後処理

customevaporated to dryness
customevaporated to dryness

出典と根拠

ORDレコード: ord-9ce98d955ee84fe4bb63bcc3f94edb73
出典データセット: uspto-grants-1976_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03931302

反応ノート

読み込み中…

参加物