Chloroacetonitrile → HCID 54476035、化合物

HRID 1580109ノート

反応式

HRID 1580109 の反応式
[CH3:1][N:2]([CH3:12])[C:3]1[CH:4]=[C:5]([OH:11])[C:6](=[CH:9][CH:10]=1)[CH:7]=[O:8].C(=O)([O-])[O-].[K+].[K+].Cl[CH2:20][C:21]#[N:22]>CC(C)=O>[CH:7]([C:6]1[CH:9]=[CH:10][C:3]([N:2]([CH3:12])[CH3:1])=[CH:4][C:5]=1[O:11][CH2:20][C:21]#[N:22])=[O:8]

参加物

5

反応物 3

HCID 7856ChloroacetonitrileHCID 11430Potassium CarbonateHCID 98153054-(dimethylamino)-2-hydroxybenzaldehyde

生成物 1

HCID 54476035HCID 54476035、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

82 parts of 4-dimethylaminosalicylaldehyde is dissolved in 500 parts by volume of acetone, then 96 parts of potassium carbonate and 45 parts of chloroacetonitrile are added and the whole is boiled under reflux for 10 hours. After the solution has been filtered it is concentrated and the crystals deposited are recrystallized from benzene with the addition of animal charcoal. 36 parts of colorless crystals of 2-formyl-5-dimethylaminophenoxyacetonitrile is obtained with a melting point of 124° to 125°C.

後処理

  1. temperatureunder reflux for 10 hours
  2. filtrationAfter the solution has been filtered it
  3. concentrationis concentrated
  4. customthe crystals deposited are recrystallized from benzene with the addition of animal charcoal

出典と根拠

ORDレコード
ord-9d1c6a998d93484390af7c4976fd287a
出典データセット
uspto-grants-1976_01
特許番号
US03932446

反応ノート

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