Nitric Acid → 5-Chloro-3-methyl-4-nitro-1-phenyl-1H-pyrazole
反応式
[Cl:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1.[N+:14]([O-])([O:16]C(=O)C)=[O:15].[N+]([O-])(O)=O>C(OC(=O)C)(=O)C>[Cl:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([CH3:13])[C:3]=1[N+:14]([O-:16])=[O:15]参加物
5
実験手順
A solution of 9.6 g (0.05 mole) of 5-chloro-3-methyl-1-phenylpyrazole and 25 ml of acetic anhydride was added at 10°C to a solution of acetyl nitrate prepared from 25 ml of 90% nitric acid and 10 ml of acetic anhydride. The solution was stirred 2 hours at 20°-30°C and carefully poured onto ice water. The solid was filtered off and washed with cold water. One recrystallization from ethanol gave long white needles of product.
後処理
- additioncarefully poured onto ice water
- filtrationThe solid was filtered off
- washwashed with cold water
- customOne recrystallization from ethanol
- customgave long white needles of product
出典と根拠
- ORDレコード
- ord-842f706eb2ed472ea0a5c413e714db82
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03932453
反応ノート
読み込み中…