Tetrahydrofuran → HCID 21433688、化合物
反応式
[C:1]([C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1)#N.[H-].[Al+3].[Li+].[H-].[H-].[H-].[O:22]1CCCC1>>[OH:9][CH:6]1[CH2:7][CH2:8][C:3]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)([CH:1]=[O:22])[CH2:4][CH2:5]1参加物
4
実験手順
A thus produced 4-cyano-4-phenylcyclohexanol (b) obtained in step (1) is directly reduced, e.g., with lithium aluminum hydride (in a solvent such as tetrahydrofuran) at elevated (reflux) temperature, to give a corresponding 4-hydroxy-1-phenyl-1-cyclohexanecarboxaldehyde (c). This compound is also prepared via the tetrahydropyranyl ether of (b).
出典と根拠
- ORDレコード
- ord-1210f3675c5c4261a0f94dd23d8c71a6
- 出典データセット
- uspto-grants-1976_01
- 特許番号
- US03932425
反応ノート
読み込み中…