Ethanol → 1-Amino-2-nitro-4-omega-cyanoacetylamino-benzene

HRID 1580769ノート

反応式

HRID 1580769 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].C(O)C.[C:15]([CH2:17][C:18](OCC)=[O:19])#[N:16]>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:18](=[O:19])[CH2:17][C:15]#[N:16])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

参加物

4

反応物 3

HCID 702EthanolHCID 7764Ethyl cyanoacetateHCID 43383702-Nitro-4-phenylenediamine

生成物 1

HCID 203760951-Amino-2-nitro-4-omega-cyanoacetylamino-benzene

実験手順

15.3 gm (0.1 mol) of 1,4-diamino-2-nitrobenzene were heated to boiling in 150 ml of ethyl cyanoacetate. Simultaneously therewith the ethanol formed during the reaction was removed by distillation. After the reaction mixture was cooled, the precipitate formed was vacuum filtered, washed with ether and recrystallized from dilute acetic acid. The product had a melting point of 218°-221°C.

後処理

  1. customwas removed by distillation
  2. temperatureAfter the reaction mixture was cooled
  3. customthe precipitate formed
  4. filtrationfiltered
  5. washwashed with ether
  6. customrecrystallized from dilute acetic acid

出典と根拠

ORDレコード
ord-33eddbc218fb477985b9c89771e72f12
出典データセット
uspto-grants-1976_01
特許番号
US03933886

反応ノート

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