Hydrogen Peroxide → HCID 20354850、化合物

HRID 1580780ノート

反応式

HRID 1580780 の反応式
[C:1]([O:4][CH:5]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:6][CH2:7][C:8]1[C:9](=[O:13])[CH2:10][CH2:11][CH:12]=1)(=[O:3])[CH3:2].[OH:19]O.[OH-].[Na+]>CO>[C:1]([O:4][CH:5]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:6][CH2:7][C:8]12[O:19][CH:12]1[CH2:11][CH2:10][C:9]2=[O:13])(=[O:3])[CH3:2]

参加物

5

反応物 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 20354852HCID 20354852、化合物

生成物 1

HCID 20354850HCID 20354850、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A stirred solution of 2-(3-acetoxyoctyl)cyclopent-2-enone (31.8 g.) [prepared as described in (f) above] in methanol (700 ml.) was treated slowly with aqueous hydrogen peroxide solution (45 ml. of "100 vol." solution) and aqueous 4N sodium hydroxide solution (15 ml.) at 5° to 10°C. and allowed to stand at room temperature for 18 hours. The solution was concentrated in vacuo (to about 100 ml. volume), and water (100 ml.) was added to the residue. The mixture was extracted with chloroform and the chloroform extract was washed with water and dried over magnesium sulphate. The solvent was removed in vacuo to give 2-(3-acetoxyoctyl)-2,3-epoxycyclopentanone (26.4 g.) which was used as starting material in the following preparation (h) of 5-acetoxy-2-(3-acetoxyoctyl)-cyclopent-2-enone without further purification.

後処理

  1. concentrationThe solution was concentrated in vacuo (to about 100 ml. volume), and water (100 ml.)
  2. additionwas added to the residue
  3. extractionThe mixture was extracted with chloroform
  4. extractionthe chloroform extract
  5. washwas washed with water
  6. dry with materialdried over magnesium sulphate
  7. customThe solvent was removed in vacuo

出典と根拠

ORDレコード
ord-0af2a2bb873b4c3595e7e19181cbcd54
出典データセット
uspto-grants-1976_01
特許番号
US03933890

反応ノート

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