Methanol → 4-[(1H-Imidazol-2-yl)sulfanyl]benzene-1,2-diamine

HRID 1580966ノート

反応式

HRID 1580966 の反応式
[NH2:1][C:2]1[CH:7]=[C:6]([S:8][C:9]2[NH:10][CH:11]=[CH:12][N:13]=2)[CH:5]=[CH:4][C:3]=1[N+:14]([O-])=O.CO>[Fe].O>[NH2:14][C:3]1[CH:4]=[CH:5][C:6]([S:8][C:9]2[NH:13][CH:12]=[CH:11][N:10]=2)=[CH:7][C:2]=1[NH2:1]

参加物

5

反応物 2

HCID 887MethanolHCID 214827775-[(1H-Imidazol-2-yl)sulfanyl]-2-nitroaniline

生成物 1

HCID 214827834-[(1H-Imidazol-2-yl)sulfanyl]benzene-1,2-diamine

試薬・触媒・溶媒 2

HCID 23925Iron触媒2 回HCID 962Water溶媒

実験手順

A mixture of 2.6 g. of 2-amino-4-(imidazol-2-ylthio)-1-nitrobenzene, 2.6 g. of iron powder and 1.3 g. ferrous sulfate in 200 ml. methanol and 50 ml. water is refluxed for 2 hours. An additional 2.6 g. of iron is added and refluxing continued for 2 hours. The mixture is filtered and the filtrate stripped to yield 1,2-diamino-4-(imidazol-2-ylthio)benzene.

後処理

  1. additionA mixture of 2.6 g
  2. temperaturerefluxing
  3. filtrationThe mixture is filtered

出典と根拠

ORDレコード
ord-0bf9b626b795444ead2349b5c0181612
出典データセット
uspto-grants-1976_01
特許番号
US03935209

反応ノート

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