HCID 22723464、化合物 → HCID 22723455、化合物
反応式
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[N:16]=[CH:17][O:18][CH:19]=1)C1C=CC=CC=1>ClCCl.[Pd]>[O:18]1[CH:19]=[C:15]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[OH:8])[N:16]=[CH:17]1参加物
4
実験手順
To a solution of the oxazole from above (1.99 g, 7.92 mmol) in dichloromethane (20 ml) is added 10% palladium on carbon (1.99 g). The mixture is put under an atmosphere of hydrogen, stirred at room temperature over night, then filtered through Celite. The solvent is removed under reduced pressure to leave 2-(oxazol-4-yl)phenol (1.15 g, 90%), which is used for the next step without further purification.
後処理
- filtrationfiltered through Celite
- customThe solvent is removed under reduced pressure
出典と根拠
- ORDレコード
- ord-28d2c149803b48fca9e0788fac35463b
- 出典データセット
- uspto-grants-2004_05
- 特許番号
- US06730792B2
反応ノート
読み込み中…