HCID 54351986、化合物 → 6-(4-Chlorophenyl)hexanoic acid
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:4][CH:3]=1>[Pd].C(OCC)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[CH:6][CH:7]=1参加物
4
実験手順
A mixture of 49.3 g (0.219 mole) of 6-(p-chlorophenyl)hex-5-enoic acid, 3.0 g of 10% Pd/C, and 300 ml of ethyl acetate was hydrogenated at 45 psi and room temperature for 20 hours. The catalyst was removed by filtration through a Celite pad, and the filtrate concentrated to give 21.3 g (43%) of V as an oil, which was used without further purification.
後処理
- customThe catalyst was removed by filtration through a Celite pad
- concentrationthe filtrate concentrated
- customto give 21.3 g (43%) of V as an oil, which
- customwas used without further purification
出典と根拠
- ORDレコード
- ord-5f1d7963ee954557a37b05ff68d7d817
- 出典データセット
- uspto-grants-1985_11
- 特許番号
- US04554276
反応ノート
読み込み中…