Water → 1-(3-Methylphenyliminomethyl)-2-nitroiminoimidazolidine

HRID 1587735ノート

反応式

HRID 1587735 の反応式
C(O[CH:4](OCC)[N:5]1[CH2:9][CH2:8][NH:7][C:6]1=[N:10][N+:11]([O-:13])=[O:12])C.[NH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=1.C(COC)OC.O>CCOCC>[CH3:24][C:20]1[CH:19]=[C:18]([N:17]=[CH:4][N:5]2[CH2:9][CH2:8][NH:7][C:6]2=[N:10][N+:11]([O-:13])=[O:12])[CH:23]=[CH:22][CH:21]=1

参加物

6

反応物 4

HCID 962WaterHCID 7934m-ToluidineHCID 80711,2-DimethoxyethaneHCID 1364034191-Diethoxymethyl-2-nitroiminoimidazolidine

生成物 1

HCID 1363314831-(3-Methylphenyliminomethyl)-2-nitroiminoimidazolidine収率 51.8%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A mixture of 2.0 g of 1-diethoxymethyl-2-nitroiminoimidazolidine, 0.92 g of m-toluidine, 5 ml of dimethoxyethane and 0.12 g of a boron trifluoride ether complex was heated under reflux for 1 hour. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and condensed. Ether was added to the resultant oily residue and the resultant crystals were separated by filtration and dried to give 1.1 g of 1-(3-methylphenyliminomethyl)-2-nitroiminoimidazolidine.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 1 hour
  3. extractionextracted with ethyl acetate
  4. washwashed with water
  5. customdried
  6. customcondensed
  7. customthe resultant crystals were separated by filtration
  8. customdried

出典と根拠

ORDレコード
ord-a8017a0832354d28a84cb41dcd8c9bb5
出典データセット
uspto-grants-1993_06
特許番号
US05219868

反応ノート

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