反応式
[CH2:1]([N:8]1[C:12](=O)[CH2:11][CH2:10][C:9]1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(O[SiH](OCC)OCC)C>C1C=CC=CC=1.CC(C)[O-].[Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-]>[CH2:1]([N:8]1[CH:12]=[CH:11][CH:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
5
反応条件
- 温度
- 60 °C
実験手順
N-benzylsuccinimide (0.38 g, 2.0 mmol), triethoxysilane (1.85 mL, 10 mmol), and titanium (IV) isopropoxide (0.06 mL, 0.2 mmol) were dissolved in C6H6 (4.0 mL) and the mixture was heated to 60 ° C. for 16 hours. The solvent was removed in vacuo and the reaction mixture was poured into a mixture of 1 M NaOH (10 mL) and THF (10 mL). This mixture was stirred for 1 hour, poured into ethyl ether (75 mL), and washed with 1 M NaOH (5×50 mL). The ether layer was dried over MgSO4, filtered, and the solvent was removed in vacuo to produce 0.29 g (91% yield) of N-benzylpyrrole as a yellow oil.
後処理
- customThe solvent was removed in vacuo
- additionthe reaction mixture was poured into a mixture of 1 M NaOH (10 mL) and THF (10 mL)
- additionpoured into ethyl ether (75 mL)
- washwashed with 1 M NaOH (5×50 mL)
- dry with materialThe ether layer was dried over MgSO4
- filtrationfiltered
- customthe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-58f0e60f495f45b2ace2c787867927c7
- 出典データセット
- uspto-grants-1993_06
- 特許番号
- US05220020
関連ノート
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