Triethylamine → HCID 19757146、化合物

HRID 1588083ノート

反応式

HRID 1588083 の反応式
[F:1][As-:2]([F:7])([F:6])([F:5])([F:4])[F:3].[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[S+:15]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[OH:29])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[OH:22].C(N([CH2:35][CH3:36])CC)C.[O:37]([CH:44]([O:46][C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)Cl)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>O1CCCC1>[F:1][As-:2]([F:7])([F:6])([F:5])([F:4])[F:3].[O:37]([CH:44]([O:46][C:36]1[CH:35]=[CH:52][CH:47]=[CH:48][CH:49]=1)[O:29][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[S+:15]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[O:8][CH:44]([O:46][C:47]1[CH:48]=[CH:49][CH:50]=[CH:51][CH:52]=1)[O:37][C:38]1[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22][CH:44]([O:46][C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)[O:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 133499351,1'-[(Chloromethylene)bis(oxy)]dibenzeneHCID 19757136HCID 19757136、化合物

生成物 1

HCID 19757146HCID 19757146、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

20 parts of tris(hydroxyphenyl)sulfonium hexafluoroarsenate are dissolved in 100 parts of tetrahydrofuran. 12.2 parts of triethylamine are added, followed dropwise by the gradual addition of 30 parts of diphenoxychloromethane, and the mixture is stirred at room temperature for 24 hours. The mixture is then washed with water, and the organic solution is dried over a molecular sieve and evaporated in a rotary evaporator. Chromatographic purification leaves 14.8 parts of the expected product. IR and NMR agree with the expected structure.

後処理

  1. washThe mixture is then washed with water
  2. customthe organic solution is dried over a molecular sieve
  3. customevaporated in a rotary evaporator
  4. customChromatographic purification

出典と根拠

ORDレコード
ord-3b04850d5672413585af27cd638ea366
出典データセット
uspto-grants-1993_06
特許番号
US05220037

反応ノート

読み込み中…