Trifluoroacetic acid → 4-(N-methyl-beta-alanyl)morpholine trifluoroacetic acid salt
反応式
C(O[C:6]([N:8](C)[CH2:9][CH2:10][C:11]([N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1)=[O:12])=O)(C)(C)C.[F:20][C:21]([F:26])([F:25])[C:22]([OH:24])=[O:23]>>[F:20][C:21]([F:26])([F:25])[C:22]([OH:24])=[O:23].[CH3:6][NH:8][CH2:9][CH2:10][C:11]([N:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1)=[O:12]参加物
3
実験手順
A solution of 4-(N-t-butoxycarbonyl-N-methyl-β-alanyl)morpholine (1.37 g) in trifluoroacetic acid (20 ml) was stirred at 0° C. for 1 hour. The solvent was evaporated to give 4-(N-methyl-β-alanyl)morpholine trifluoroacetic acid salt (1.44 g).
後処理
- customThe solvent was evaporated
出典と根拠
- ORDレコード
- ord-b449b4003d264743b42a803bfbe7ace6
- 出典データセット
- uspto-grants-1993_06
- 特許番号
- US05223489
反応ノート
読み込み中…