Thionyl Chloride → HCID 178447883、化合物

HRID 1589738ノート

反応式

HRID 1589738 の反応式
O=S(Cl)[Cl:3].[CH2:5]([C@H:8]1[CH2:13][CH2:12][C@H:11]([C:14]2[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)[CH2:6][CH3:7]>>[CH2:5]([C@H:8]1[CH2:13][CH2:12][C@H:11]([C:14]2[CH:22]=[CH:21][C:17]([C:18]([Cl:3])=[O:19])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)[CH2:6][CH3:7]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 178447888HCID 178447888、化合物

生成物 1

HCID 178447883HCID 178447883、化合物収率 96.2%

実験手順

In 75 cm3 (1.0 mol) of SOCl2, 128 g (0.52 mol) of 4-(trans-4'-propylcyclohexyl) benzoic acid was refluxed for 3 hours. The excess SOCl2 was distilled off under a reduced pressure and the residue was distilled under reduced pressure (158° C./3.0 mmHg) to yield 133 g (0.50 mol) of 4-(trans-4'-propylcyclohexyl) benzoic acid chloride.

後処理

  1. distillationThe excess SOCl2 was distilled off under a reduced pressure
  2. distillationthe residue was distilled under reduced pressure (158° C./3.0 mmHg)

出典と根拠

ORDレコード
ord-8eaca0e6aa924d44805999afc6b806fe
出典データセット
uspto-grants-1993_04
特許番号
US05200110

反応ノート

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