関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Methyl Acrylate | HCID 7294 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2,5-Dimethyl-2,5-dihydroxy-1,4-dithiane | HCID 62105 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Methyl 3-acetonylmercaptopropionate | HCID 15030534 | — |
反応手順
90.1 g (0.5 mol) of 2,5-dihydroxy-2,5-dimethyl-1,4-dithiane are initially introduced into 100 ml of absolute tetrahydrofuran. 1.0 g of piperidine is then added, and 94.7 g (0.945 mol) of methyl acrylate are added dropwise at 10°-15° C, during which process another two portions of 0.5 g of piperidine are added at the same time. The mixture is subsequently stirred for 60 minutes at 60° C. It is allowed to cool and introduced into 500 ml of water.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05201936 |
|---|
| 出典データセット | uspto-grants-1993_04 |
|---|
| ORD ID | ord-d63fb943fd6245dab14c117df0577849 |
|---|
| 出典メモ | uspto-grants-1993_04 |
|---|
