反应详情

温度

60 °C

90.1 g (0.5 mol) of 2,5-dihydroxy-2,5-dimethyl-1,4-dithiane are initially introduced into 100 ml of absolute tetrahydrofuran. 1.0 g of piperidine is then added, and 94.7 g (0.945 mol) of methyl acrylate are added dropwise at 10°-15° C, during which process another two portions of 0.5 g of piperidine are added at the same time. The mixture is subsequently stirred for 60 minutes at 60° C. It is allowed to cool and introduced into 500 ml of water.

1. additionare added at the same time
2. temperatureto cool