Diaminomaleonitrile → HCID 68546627、化合物

HRID 1591079ノート

反応式

HRID 1591079 の反応式
[NH2:1]/[C:2](/[C:7]#[N:8])=[C:3](\[NH2:6])/[C:4]#[N:5].[Cl:9][C:10]1[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[CH:15]=[C:14]([Cl:22])[C:11]=1[CH:12]=O>CO>[NH2:1][C:2]([C:7]#[N:8])=[C:3]([N:6]=[CH:12][C:11]1[C:14]([Cl:22])=[CH:15][C:16]([C:18]([F:19])([F:20])[F:21])=[CH:17][C:10]=1[Cl:9])[C:4]#[N:5]

参加物

4

反応物 2

HCID 2723951DiaminomaleonitrileHCID 147939142,6-Dichloro-4-(trifluoromethyl)benzaldehyde

生成物 1

HCID 68546627HCID 68546627、化合物収率 77.3%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Diaminomaleonitrile (4.4 g, 0.04 mol) was dissolved in methanol (100 ml) and 2,6-dichloro-4-trifluoromethylbenzaldehyde (9.6 g, 0.04 mol) was added with stirring at ambient temperature. The reaction mixture was stirred for 30 minutes and heated at reflux for 1 hour. After cooling to 10° C. a solid which had separated was filtered off to give 1-amino-2-(2,6-dichloro-4-trifluoromethylbenzylideneamino)- 1,2-dicyanoethylene (10.3 g) as a yellow crystalline solid, m.p. 218°-219° C.

後処理

  1. stirringThe reaction mixture was stirred for 30 minutes
  2. temperatureheated
  3. temperatureat reflux for 1 hour
  4. temperatureAfter cooling to 10° C. a solid which
  5. customhad separated
  6. filtrationwas filtered off

出典と根拠

ORDレコード
ord-9aeb0475165b4aa1a188cc5be56bc68a
出典データセット
uspto-grants-1993_04
特許番号
US05206257

反応ノート

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