Hydrochloric Acid → 2-[4-(Aminomethyl)phenyl]ethan-1-ol

HRID 1591190ノート

反応式

HRID 1591190 の反応式
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8][OH:9])=[CH:5][CH:4]=1)#[N:2].Cl>C(O)C.[Pd]>[OH:9][CH2:8][CH2:7][C:6]1[CH:10]=[CH:11][C:3]([CH2:1][NH2:2])=[CH:4][CH:5]=1

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 28008154-(2-Hydroxyethyl)benzonitrile

生成物 1

HCID 226014582-[4-(Aminomethyl)phenyl]ethan-1-ol

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 0.74 g (0.005 mol) of p-cyanophenethyl alcohol in 50 ml of ethanol containing 10 ml of concentrated hydrochloric acid was hydrogenated at 30 psi using 0.1 g 5% Pd/C for 72 hours. The catalyst was removed by filtration and the solvent was removed under reduced pressure.

後処理

  1. customfor 72 hours
  2. customThe catalyst was removed by filtration
  3. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-0575f38d34cd444d949321fac434cb54
出典データセット
uspto-grants-1993_04
特許番号
US05206240

反応ノート

読み込み中…