Methyl iodide → 1-(2,4-Difluorophenyl)-2-(pyridin-3-yl)propan-1-one
反応式
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:17])[CH2:10][C:11]1[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=1.I[CH3:19]>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:17])[CH:10]([C:11]1[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=1)[CH3:19]参加物
3
実験手順
Methylation of the product of part (i) (5.0 g) with iodomethane (7.60 g) according to the method of Example 11(ii) gave the title compound as an oil (3.90 g) which was used directly in the next stage.
出典と根拠
- ORDレコード
- ord-fb654f5d6f7d43dc8a492bf02a39af0c
- 出典データセット
- uspto-grants-1993_04
- 特許番号
- US05206364
反応ノート
読み込み中…