Water → 145486-31-3

HRID 1591488ノート

反応式

HRID 1591488 の反応式
O.[CH2:2]([O:9][C:10]([CH3:14])([CH:12]=C)[CH3:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.I([O-])(=O)(=O)=[O:16].[Na+]>[Os](=O)(=O)(=O)=O.O1CCOCC1>[CH2:2]([O:9][C:10]([CH3:11])([CH3:14])[CH:12]=[O:16])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

参加物

6

反応物 3

HCID 962WaterHCID 10487510HCID 10487510、化合物HCID 23667635Sodium periodate

生成物 1

HCID 10986836145486-31-3収率 37%

試薬・触媒・溶媒 2

HCID 30318Osmium Tetroxide触媒HCID 312751,4-Dioxane溶媒

実験手順

A mixture of 100 mL of water, 300 mL of dioxane, 20 g (0.11 mol) of 2-benzyloxy-2-methyl-3-butene and 1 g of osmium tetroxide was stirred at room temperature for 30 minutes then 51 g (0.22 mol) of finely ground sodium periodate was added in portions over 30 minutes. Stirring was continued for 2 hours then the mixture filtered and the filtrate extracted with several portions of ether. The combined extracts were dried over magnesium sulfate, filtered and the filtrate concentrated under vacuum. Distillation afforded 7.3 g (0.041 mol,37%) of product, b.p. 85°-88° C. (2 mm).

後処理

  1. stirringStirring
  2. waitwas continued for 2 hours
  3. filtrationthe mixture filtered
  4. extractionthe filtrate extracted with several portions of ether
  5. dry with materialThe combined extracts were dried over magnesium sulfate
  6. filtrationfiltered
  7. concentrationthe filtrate concentrated under vacuum
  8. distillationDistillation

出典と根拠

ORDレコード
ord-aad0df56932641faa355f007c32be21b
出典データセット
uspto-grants-1993_04
特許番号
US05206235

反応ノート

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