HCID 25248372、化合物 → HCID 19627217、化合物
反応式
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>CCO.[Pd]>[F:1][C:2]1[CH:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1参加物
4
実験手順
2-Fluoro-4-nitro-1-phenoxybenzene and 7.2 g of 10% Pd/C were dissolved in 200 mL EtOH and stirred under 1 atmosphere of H2 overnight. The reaction mixture was filtered through Celite with the aid of 50 mL EtOH and concentrated to provide 3-fluoro-4-phenoxybenzenamine as an oil which was used in Step C without further purification.
後処理
- filtrationThe reaction mixture was filtered through Celite with the aid of 50 mL EtOH
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-59ba03bb420749c99fbb16526e42678d
- 出典データセット
- uspto-grants-2007_11
- 特許番号
- US07294616B2
反応ノート
読み込み中…