HCID 21706478、化合物 → HCID 21706521、化合物
反応式
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([CH2:7][N:8]2[CH:13]=[CH:12][C:11]([CH:14]=[CH2:15])=[C:10]([N+:16]([O-])=O)[C:9]2=[O:19])=[CH:5][CH:4]=1>C(O)C.[Pd]>[NH2:16][C:10]1[C:9](=[O:19])[N:8]([CH2:7][C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:21][CH:20]=2)[CH:13]=[CH:12][C:11]=1[CH2:14][CH3:15]参加物
4
実験手順
A mixture of 1-(4-methoxybenzyl)-4-vinyl-3-nitro-2-pyridone (0.21 g, 0.73 mmol) in ethanol (30 mL) with 10% Pd/C (0.26 g) was hydrogenated at 40 psi in a Parr apparatus for 4 hours. The catalyst was removed by filtration and the solvent was evaporated to give 3-amino-1-(4-methoxybenzyl)-4-ethyl-2-pyridone (0.17 g, 0.56 mmol, 76%).
後処理
- customThe catalyst was removed by filtration
- customthe solvent was evaporated
出典と根拠
- ORDレコード
- ord-1f30aef376a14d16a2eeb56635388c27
- 出典データセット
- uspto-grants-2001_09
- 特許番号
- US06284768B1
反応ノート
読み込み中…