2-(2,4-Bis(benzyloxy)phenyl)ethanol → 4-(2-Hydroxyethyl)benzene-1,3-diol

HRID 1595484ノート

反応式

HRID 1595484 の反応式
C([O:8][C:9]1[CH:14]=[C:13]([O:15]CC2C=CC=CC=2)[CH:12]=[CH:11][C:10]=1[CH2:23][CH2:24][OH:25])C1C=CC=CC=1>C(OCC)(=O)C.[Pd]>[OH:8][C:9]1[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:10]=1[CH2:23][CH2:24][OH:25]

参加物

4

反応物 1

HCID 148029092-(2,4-Bis(benzyloxy)phenyl)ethanol

生成物 1

HCID 134863604-(2-Hydroxyethyl)benzene-1,3-diol収率 99.3%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

3.7 g (11.1 mmole) 2-[2,4-di(benzyloxy)phenyl]-1-ethanol was hydrogenated in 100 ml ethyl acetate using Pd/C (10%) as catalyst. The reaction mixture was filtered and the filtrate was evaporated in vacuo to give 1.7 g (yield 99%) of 2-(2,4-dihydroxyphenyl)-1-ethanol.

後処理

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated in vacuo

出典と根拠

ORDレコード
ord-f6ad53db194f46bead28d4ad27118587
出典データセット
uspto-grants-2001_09
特許番号
US06288096B1

反応ノート

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