Nitric Acid → HCID 21698918、化合物

HRID 1597184ノート

反応式

HRID 1597184 の反応式
[F:1][C:2]1[C:12]([N:13]2[C:21](=[O:22])[C:20]3[CH2:19][CH2:18][CH2:17][CH2:16][C:15]=3[C:14]2=[O:23])=[CH:11][C:5]2[NH:6][C:7](=[O:10])[CH2:8][O:9][C:4]=2[CH:3]=1.[N+:24]([O-])([OH:26])=[O:25]>C(O)(=O)C>[F:1][C:2]1[C:12]([N:13]2[C:21](=[O:22])[C:20]3[CH2:19][CH2:18][CH2:17][CH2:16][C:15]=3[C:14]2=[O:23])=[C:11]([N+:24]([O-:26])=[O:25])[C:5]2[NH:6][C:7](=[O:10])[CH2:8][O:9][C:4]=2[CH:3]=1

参加物

4

反応物 2

HCID 944Nitric AcidHCID 137721852-(7-Fluoro-3-oxo-4H-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydroisoindole-1,3-dione

生成物 1

HCID 21698918HCID 21698918、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

2-[7-Fluoro-2H-1,4-benzoxazine-3(4H)-on-6-yl]-4,5,6,7-tetrahydro-2H-isoindole-1,3-dione (1.0 g) was stirred in acetic acid (20 ml) and fuming nitric acid (8 ml) was slowly added. Solution was stirred at ambient temperature for 1 hr and the clear solution was added to ice-water. Light yellow precipitate was separated by filtration to afford the title compound (0.95 g).

後処理

  1. customLight yellow precipitate was separated by filtration

出典と根拠

ORDレコード
ord-0908b008f6184d7999c0f8e1446dad34
出典データセット
uspto-grants-2001_09
特許番号
US06294503B1

反応ノート

読み込み中…