HCID 11063236、化合物 → Ethyl 2-(1-cyanocyclohexyl)acetate

HRID 1597676ノート

反応式

HRID 1597676 の反応式
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH:11]=[CH:10][CH2:9][CH:8]=[CH:7]1)[CH3:2]>[Pd].CO>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH3:2]

参加物

4

反応物 1

HCID 11063236HCID 11063236、化合物

生成物 1

HCID 10965422Ethyl 2-(1-cyanocyclohexyl)acetate収率 94.3%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Added 1% Pd/C catalyst (1.67 g, 0.157 mmol) to a solution of (1-cyanocyclohexa-2,5-dienyl)acetic acid ethyl ester (3.00 g, 15.7 mmol) in MeOH (75 mL). After shaking the reaction under 20 psi H2 at room temperature for 2 hours, the pressure was slowly released. The reaction was filtered and concentrated under reduced pressure to afford 2.89 g (94%) of product as an oil.

後処理

  1. customthe reaction under 20 psi H2 at room temperature for 2 hours
  2. filtrationThe reaction was filtered
  3. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-4ed91b471ba2422a901d6ef561fb6306
出典データセット
uspto-grants-2001_09
特許番号
US06294690B1

反応ノート

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