2,4-anhydro-3,5-bis-O-(phenylmethyl)-D-lyxonic acid methyl ester → HCID 15725611、化合物
反応式
[CH3:1][O:2][C:3]([C@H:5]1[O:16][C@H:15]([CH2:17][O:18]CC2C=CC=CC=2)[C@@H:6]1[O:7]CC1C=CC=CC=1)=[O:4].[H][H]>[OH-].[OH-].[Pd+2].CO>[CH3:1][O:2][C:3]([C@H:5]1[O:16][C@H:15]([CH2:17][OH:18])[C@@H:6]1[OH:7])=[O:4]参加物
5
実験手順
A slurry of 1.01 g of 2,4-anhydro-3,5-bis-O-(phenylmethyl)-D-lyxonic acid methyl ester (prepared by the procedure in Tetrahedron Letters, Vol 31, No. 33, p4787, 1990), 0.253 g of palladium hydroxide on carbon, and 30 ml of methyl alcohol is hydrogenated under a balloon of hydrogen (1 atm.) for2.5 hours. The mixture is filtered through diatomaceous earth, washed with ethyl acetate and ethyl alcohol, and concentrated in vacuo to give 0.460 gof the desired product.
後処理
- custom5 hours
- filtrationThe mixture is filtered through diatomaceous earth
- washwashed with ethyl acetate and ethyl alcohol
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-cee4c68e87244b10ab4ca44da5a48200
- 出典データセット
- uspto-grants-1998_04
- 特許番号
- US05744465
反応ノート
読み込み中…