Dimethylformamide → 2,6-Dibromo-1,4-phenylenediamine
反応式
[Br:1][C:2]1[CH:8]=[C:7]([N+:9]([O-])=O)[CH:6]=[C:5]([Br:12])[C:3]=1[NH2:4].C(OCC)(=O)C.CN(C)C=O.[H][H]>C(O)C.[Pt]>[NH2:4][C:3]1[C:2]([Br:1])=[CH:8][C:7]([NH2:9])=[CH:6][C:5]=1[Br:12]参加物
7
実験手順
3.0 g of 2,6-dibromo-4-nitroaniline are dissolved in 150 ml of ethanol, 150 ml of ethyl acetate and 30 ml of dimethylformamide and, after addition of 0.5 g of platinum on carbon (5%), hydrogenated under a pressure of 1.5 bar of hydrogen in a Parr apparatus at room temperature for 1 hour. Cooling is followed by filtration, the solvent is distilled off in a rotary evaporator, and the residue is purified by column chromatography.
後処理
- temperatureCooling
- filtrationis followed by filtration
- distillationthe solvent is distilled off in a rotary evaporator
- customthe residue is purified by column chromatography
出典と根拠
- ORDレコード
- ord-b1ee345baeaf4d92a55db75fab27a8a9
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05977102
反応ノート
読み込み中…