Rutin → HCID 66688099、化合物

HRID 1601419

反応式

HRID 1601419 の反応式
C[C@@H]1O[C@@H](OC[C@H]2O[C@@H]([O:16][C:17]3[C:26](=[O:27])[C:25]4[C:24]([OH:28])=[CH:23][C:22]([OH:29])=[CH:21][C:20]=4[O:19][C:18]=3[C:30]3[CH:31]=[CH:32][C:33]([OH:37])=[C:34]([OH:36])[CH:35]=3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O>Cl>[CH:31]1[C:30]([C:18]2[O:19][C:20]3[CH:21]=[C:22]([OH:29])[CH:23]=[C:24]([OH:28])[C:25]=3[C:26](=[O:27])[C:17]=2[OH:16])=[CH:35][C:34]([OH:36])=[C:33]([OH:37])[CH:32]=1.[C:25]1([CH:26]=[CH:17][C:18]([C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)=[O:19])[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

参加物

3

反応物 1

HCID 5280805Rutin

生成物 1

HCID 66688099HCID 66688099、化合物

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

One hundred (100) grams of rutin was dissolved in one (1) liter of lN hydrochloric acid at a temperature of 80-90° C., and allowed to react at that temperature for a total of 3 hours, forming a yellowish-brown precipitate. The resultant mixture was allowed to cool to room temperature and the precipitate removed by filtration, with continual washing with distilled water, until a pH of 6.0-6.5 was obtained. The precipitate was dried and redissolved in 90% ethyl alcohol, and filtered to remove impurities, with the alcohol subsequently distilled off. The remaining precipitate was then suspended in 200 ml of distilled water. Gradually, a solution of lN sodium hydroxide was added, until a clear, golden-brown solution without a precipitate was obtained. This solution was oven dried at a temperature of 70-80° C., yielding a brown powder of quercetin chalcone. The quercetin chalcone produced by this method was soluble in distilled water, a concentration of 20% quercetin chalcone in water was readily produced. Quercetin, on the other hand, was almost totally insoluble in water.

後処理

  1. customto react at that temperature for a total of 3 hours
  2. customforming a yellowish-brown precipitate
  3. customthe precipitate removed by filtration
  4. washwith continual washing with distilled water, until a pH of 6.0-6.5
  5. customwas obtained
  6. customThe precipitate was dried
  7. dissolutionredissolved in 90% ethyl alcohol
  8. filtrationfiltered
  9. customto remove impurities
  10. distillationwith the alcohol subsequently distilled off
  11. additionGradually, a solution of lN sodium hydroxide was added
  12. customuntil a clear, golden-brown solution without a precipitate was obtained
  13. customdried at a temperature of 70-80° C.

出典と根拠

ORDレコード
ord-ef6df22de4db4012ab484d280251b9dc
出典データセット
uspto-grants-1999_11
特許番号
US05977184

関連ノート

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