N-bromobutanimide → HCID 19611656、化合物

HRID 1602393ノート

反応式

HRID 1602393 の反応式
[F:1][C:2]1[C:10]2[O:9][CH:8]=[CH:7][C:6]=2[C:5]([CH3:11])=[CH:4][CH:3]=1.[Br:12]N1C(=O)CCC1=O>C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:11][C:5]1[C:6]2[CH:7]=[CH:8][O:9][C:10]=2[C:2]([F:1])=[CH:3][CH:4]=1

参加物

5

反応物 2

HCID 67184N-bromobutanimideHCID 196116757-Fluoro-4-methylbenzofuran

生成物 1

HCID 19611656HCID 19611656、化合物収率 108%

試薬・触媒・溶媒 2

HCID 7187Benzoyl Peroxide触媒HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 7-fluoro-4-methyl-benzofuran (14.2 g), N-bromosuccinimide (19.7 g), benzoyl peroxide (0.5 g) and carbon tetrachloride (600 ml) was heated under reflux under the illumination of an 80 W flood lamp for 20 h. The mixture was cooled, and filtered and the filtrate evaporated to dryness to give the title compound as a pale orange oil (23.4 g)

後処理

  1. temperaturewas heated
  2. temperatureunder reflux under the illumination of an 80 W flood lamp for 20 h
  3. temperatureThe mixture was cooled
  4. filtrationfiltered
  5. customthe filtrate evaporated to dryness

出典と根拠

ORDレコード
ord-e8a19b4b22b8489aa89afa0e57ccee9b
出典データセット
uspto-grants-1999_11
特許番号
US05981572

反応ノート

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