関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Hydrogen iodide | HCID 24841 | — |
| 反応物 | 1,3,5-Trimethoxyxanthone | HCID 11953368 | — |
| 反応物 | Sodium Bisulfite | HCID 23665763 | — |
| 生成物 | 1,3,5-Trihydroxyxanthone | HCID 5281663 | — |
反応手順
A mixture of compound 19 (1.9 g, 6.64 mmol) phenol (42 ml) and HI (35 ml) was refluxed at 160° C. for 8 hour and the reaction mixture was poured into aqueous NaHSO3 solution. The resulting yellow precipitate, was collected, purified by silica gel column chromatography (CH2Cl2 --MeOH, 4:1), and crystallized from methanol to give pale yellow needles 20, 1.41 g (5.78 mmol, 87%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05981774 |
|---|
| 出典データセット | uspto-grants-1999_11 |
|---|
| ORD ID | ord-6001ba9a298d4a4f9e40bc3475f83e36 |
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| 出典メモ | uspto-grants-1999_11 |
|---|
