2'-Bromoacetophenone → 3-Phenylimidazo[5,1-b]thiazole

HRID 1603494ノート

反応式

HRID 1603494 の反応式
C(O[C:6]([NH:8][CH2:9][C:10](=[S:12])[NH2:11])=O)(C)(C)C.Br[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[C:20](=O)[CH3:21]>>[C:15]1([C:20]2[N:11]3[CH:6]=[N:8][CH:9]=[C:10]3[S:12][CH:21]=2)[CH:16]=[CH:17][CH:18]=[CH:19][CH:14]=1

参加物

3

反応物 2

HCID 750602'-BromoacetophenoneHCID 5324304tert-butyl N-(carbamothioylmethyl)carbamate

生成物 1

HCID 234493013-Phenylimidazo[5,1-b]thiazole収率 66%

実験手順

The same procedure as in Preparation 10 was repeated except that 1.9 g of (N-t-butoxycarbonylamino) acetothioamide and 2.49 g of 2'-bromoacetophenone were used, thereby obtaining 1.32 g of the title compound.

後処理

  1. customThe same procedure as in Preparation 10

出典と根拠

ORDレコード
ord-3f00dd7ac2f5416d86580babc3c1595f
出典データセット
uspto-grants-1999_11
特許番号
US05990101

反応ノート

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