Ethanol → HCID 19605320、化合物

反応式

COC1C=CC(CN2C(=O)[CH:11]3[CH:14]=[CH:15][CH:16]=[CH:17][C:10]3([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])C2=O)=CC=1.O.[NH2:28]N.[CH2:30]([OH:32])C>>[CH3:30][O:32][C:15]1[CH:14]=[CH:11][C:10]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][NH2:28])=[CH:17][CH:16]=1

参加物

反応物 3

HCID 702Ethanol

HCID 24654Hydrazine hydrate (1:1)

HCID 67586558N-(4-methoxybenzyl)-1-hexyl phthalimide

生成物 1

HCID 19605320HCID 19605320、化合物

実験手順

N-(4-methoxybenzyl)-1-hexyl phthalimide (19.9 g, 60 mmol) was dissolved in ethanol (300 ml) and hydrazine monohydrate (8.9 g, 0.11 mol) was added. The mixture was refluxed for 3 hours, filtered, the residue washed with ethanol and the filtrate evaporated. The residue was taken up in diethyl ether, filtered and the residue washed well with ether. Evaporation of the filtrate gave a yellow oil which was purified by distillation to give a clear oil bp 108-110° C., 0.02 mbar.