Acetic Acid → Ethyl 3-(2-methoxyanilino)-2-methyl-2-butenoate
反応式
[CH3:1][O:2][C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].C(O)(=O)C.[C:14]([CH:17]([CH3:23])[C:18]([O:20][CH2:21][CH3:22])=[O:19])(=O)[CH3:15]>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH:5][C:14]([CH3:15])=[C:17]([CH3:23])[C:18]([O:20][CH2:21][CH3:22])=[O:19]参加物
5
実験手順
A mixture of 2-methoxyaniline (10 g), acetic acid (1 ml) and ethyl 2-acetylpropionate (12.3 g) in benzene (30 ml) was refluxed for 24 hours, and then the solvent was removed to give crude ethyl 3-(2-methoxyanilino)-2-methyl-2-butenoate, which was used as a starting compound at the following example without further purification.
後処理
- temperaturewas refluxed for 24 hours
- customthe solvent was removed
出典と根拠
- ORDレコード
- ord-074ae69a55d343abad7b707f2f790133
- 出典データセット
- uspto-grants-1999_11
- 特許番号
- US05994368
反応ノート
読み込み中…